[Myelofibrosis with myeloid metaplasia].

نویسندگان

  • S Juárez Alonso
  • A D Pérez-Navarro
  • J M Montero García
  • J Ortiz Vázquez
چکیده

Introduction Myelofibrosis with myeloid metaplasia (MMM) represents both agnogenic myeloid metaplasia (AMM) and the fibrotic stages of polycythemia vera (PV) and essential thrombocythemia (ET). The latter two conditions are also referred to as post polycythemic myelofibrosis (PPM) and post thrombocythemic myelofibrosis (PTM). MMM is currently classified under the broad category of chronic myeloid disorders (CMD). Classification of the CMDs is based on certain molecular, cytogenetic, morphologic, and clinical characteristics. In the context of a CMD, the demonstration of the bcr/abl genetic translocation between chromosomes 9 and 22 mandates a diagnosis of chronic myelocytic leukemia (CML). The bcr/abl–negative group may be divided into two major subgroups; the myelodysplastic syndromes (MDS) and the chronic myeloproliferative disorders (CMPD). MMM is classified under the latter group along with PV and ET.

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عنوان ژورنال:
  • Revista clinica espanola

دوره 117 4  شماره 

صفحات  -

تاریخ انتشار 1970